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Bactrim for chronic bronchitis and bronchodilator treatment of chronic bronchitis, but, if available, it is generally recommended that ciprofloxacin not be used. The use of ciprofloxacin, a known human carcinogen, in the treatment of severe or progressive COPD has been recommended only when the severity of lung disease requires such treatment.
Antihistamines
The antimicrobial agent achlorpropion (Claritin®), marketed as Aleve® by Novartis Pharmaceuticals, is a second generation, short acting, nonselective diuretic used as a short acting antihistamine for preventing or treating nasal allergy symptoms, and for reducing itching.
It also has been approved for use in patients with moderate and severe bronchitis as an adjuvant medication to increase antibiotic and anticholinergic effect in the treatment of patients with cystic fibrosis and acute bronchiolitis. However, because anaphylaxis to the drug can occur at same as it can in the face of nasal administration, Aleve® must not be given sublingually in patients who are not allergic to the compound. When Aleve® is administered with a nasogastric or oropharyngeal route in such patients the drug must be administered cautiously and under close medical supervision to avoid an accidental aspiration of the drug into stomach.
Aleve® does not produce hypotension, it has been reported as an additive in the treatment of bronchial asthma exacerbations. Aleve® has an excellent safety reputation. In the adult treatment category, clinical trials in patients with moderate to severe bronchitis showed that Aleve® reduces both the duration of severe bronchitis and the number of days between exacerbation and the cessation of therapy. In adult treatment category, one uncontrolled trial showed that Aleve® is as effective the commonly prescribed short acting drug, albuterol, in relieving the symptoms of chronic bronchitis associated with asthma. When used in the combination with albuterol, however, Aleve® might need special control and monitoring to maintain adequate bronchodilator effect.
Drugs That Are Prescribed Or Not For Chronic Bronchitis
Antihistamine: All medications prescribed for chronic bronchitis should be avoided by the patient because it will increase the risk of allergic reactions. Therefore, a doctor in charge of the patient care and monitoring of the patient is not advised to add an antihistamine a course of antibiotics in patient who has no other allergic reaction to antibiotics and who will not be sensitized or sensitive to those drugs.
Antihistamine: The most potent anticholinergic available is alprazolam a generic drug is chlornaphalcon: Chlorpheniramine and cimbalanib, sold as Claritin® or Aleve®, are sold as a systemic therapy for asthma. Chlorpheniramine is an over-the-counter, non-prescription medicine for treating severe, recurrent allergic rhinitis or allergies and other chronic asthma symptoms as noted below. Claritin is an over-the-counter, non-prescription medicine used for the treatment of recurrent chronic asthma.
Chlorpheniramine acts by inhibiting acetylcholine and histamine synthesis. It has few cardiovascular side effects and does not cause high blood pressure.
Claritin acts by inhibiting acetylcholine, nitric oxide and prostacyclin. It has few cardiovascular side effects and does not cause blood pressure elevation or fainting attacks.
Both of these drugs are often abused or misused, and thus they should be avoided by the patient.
Antihistamine: A drug that is available without a prescription, but is available without a particular indication, such as the cough suppressant droperidol, appetite phentermine and the anorectic drug guanfacine, is not recommended for use in patients with chronic bronchitis since such treatment tends to cause more side effects than the other drug mentioned above. use of antihistamines should not be continued beyond the first week of hospitalization if the patient is admitted for non-respiratory-related symptoms after antibiotic therapy has been started.
Antihistamine Drug Combinations
A combination of antibiotics in with an antibiotic that is not the antibacterial agent indicated for treating the patient is not recommended.
The following example illustrates use of the antihistamine aniprazole and a beta-lactam antibiotic to treat patients with severe bronchitis; however, this combination should generally not be used. This case highlights the need to use drugs in a manner that minimizes potential risks.
Example 2: A 41- year-old male presents to the emergency room, complaining of a severe acute cough associated with chest pains which, two days before presentation, had been reduced to short, controlled cough.
